Deep Learning-Based Lung Cancer Detection Using CT Scan Images: A Comparative Study of VGG16, ResNet50, and DenseNet121

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Suhas Mohite
Amol Kadam
Sunil Kadam
Chetan More
Vinod Patil
Sandip Chavan

Abstract

Lung cancer is a major problem because it kills more people every year than any other type of cancer. If we can find the abnormal areas early, people are much more likely to recover. Doctors usually use a type of scan called a CT scan to look for these abnormal areas. The problem is that reviewing all the scan images is very tedious, and even experienced doctors can miss something. We wanted to see whether computers could help with this task. We tried using three kinds of computer programs, VGG16, ResNet50 and DenseNet121, to look at the pictures from the scan. We used a collection of pictures called the LIDC-IDRI collection to teach the computers what to look for. DenseNet121 performed best at identifying the regions. We think this is because it is good at using the information it has to make decisions. We also used a tool called Grad-CAM to see what the computers were actually looking at. It showed that the better programs focused on the abnormal areas, not just the normal tissue. Our results show that using computers to help with this task is promising, and it could help doctors make better decisions. We also know there is still a lot of work to do to make it perfect.

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[1]
Suhas Mohite, Amol Kadam, Sunil Kadam, Chetan More, Vinod Patil, and Sandip Chavan , Trans., “Deep Learning-Based Lung Cancer Detection Using CT Scan Images: A Comparative Study of VGG16, ResNet50, and DenseNet121”, IJITEE, vol. 15, no. 9, pp. 17–22, Aug. 2026, doi: 10.35940/ijitee.J1301.15090826.
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References

Geppert J, Asgharzadeh A, Brown A, et al. Software using artificial intelligence for nodule and cancer detection in CT lung cancer screening: systematic review of test accuracy studies. Thorax. 2024;79(11):1040–1049.DOI: 10.1136/thorax-2024-221662

Gao J, Jiang Q, Zhou B, Chen D. Lung Nodule Detection using Convolutional Neural Networks with Transfer Learning on CT Images. Current Medical Imaging Reviews. 2021;17(6):814–824.DOI: 10.2174/1386207323666200714002459

Kumaran, Y. S., et al. (2024). Explainable lung cancer classification with ensemble transfer learning of VGG16, ResNet50 and InceptionV3 using Grad-CAM. BMC Medical Imaging, 24, 176. DOI: 10.1186/s12880-024-01345-x

Gao C, Wu L, Wu W, et al. Deep learning in pulmonary nodule detection and segmentation: a systematic review. European Radiology. 2025; 35:255–266.DOI: 10.1007/s00330-024-10907-0

Gao J, Jiang Q, Zhou B, Chen D. Lung Nodule Detection using Convolutional Neural Networks with Transfer Learning on CT Images. Current Medical Imaging Reviews. 2021;17(6):814–824.DOI: 10.2174/1386207323666200714002459

Zafaranchi A, Lizzi F, Retico A, Scapicchio C, Fantacci ME. Explainability Applied to a Deep-Learning-Based Algorithm for Lung Nodule Segmentation. Proceedings of the International Conference on Pattern Recognition Applications and Methods (ICPRAM). 2024. DOI: 10.5220/0013014600003837

Wulaningsih W, Villamaria C, Akram A, et al. Deep Learning Models for Predicting Malignancy Risk in CT-Detected Pulmonary Nodules: A Systematic Review and Meta-analysis. Lung. 2024; 202:625–636. DOI: 10.1007/s00408-024-00706-1

Saied M, Raafat M, Yehia S, Khalil MM. Efficient pulmonary nodule classification using radiomics and different artificial intelligence strategies. Insights into Imaging. 2023; 14:91.DOI: 10.1186/s13244-023-01441-6

Dai, Y., et al. (2023). MS-Net: Learning to assess the malignant status of a lung nodule by a radiologist and her peers. Journal of Applied Clinical Medical Physics.DOI: 10.1002/acm2.13964

Eliwa, A. A., et al. (2025). Enhancing Skin Cancer Diagnosis Through Fine-Tuning of Pretrained Models: A Two-Phase Transfer Learning Approach. International Journal of Breast Cancer.DOI: 10.1155/ijbc/4362941

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